製品: CCL27 Antibody
カタログ: DF9916
タンパク質の説明: Rabbit polyclonal antibody to CCL27
アプリケーション: WB IHC
反応性: Human
分子量: 13 kDa; 13kD(Calculated).
ユニプロット: Q9Y4X3
RRID: AB_2843110

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
CCL27 Antibody detects endogenous levels of total CCL27.
RRID:
AB_2843110
引用形式: Affinity Biosciences Cat# DF9916, RRID:AB_2843110.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ALP; C-C motif chemokine 27; CC chemokine ILC; Ccl27; CCL27_HUMAN; Chemokine (C-C motif) ligand 27; CTACK; CTAK; Cutaneous T cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL 11 R alpha locus chemokine; IL-11 R-alpha-locus chemokine; ILC; PESKY; SCYA27; Skinkine; Small inducible cytokine A27; small inducible cytokine subfamily A (Cys-Cys), member 27; Small-inducible cytokine A27;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9Y4X3 CCL27_HUMAN:

Testis, thymus, placenta, ovary and skin.

タンパク質配列:
MKGPPTFCSLLLLSLLLSPDPTAAFLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG

PTMs - Q9Y4X3 基板として

Site PTM Type Enzyme
K45 Ubiquitination

研究背景

機能:

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Testis, thymus, placenta, ovary and skin.

サブユニット構造:

Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization.

タンパク質ファミリー:

Belongs to the intercrine beta (chemokine CC) family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

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