製品: SCNM1 Antibody
カタログ: DF9928
タンパク質の説明: Rabbit polyclonal antibody to SCNM1
アプリケーション: WB IHC
反応性: Human, Rat, Monkey
予測: Bovine, Horse, Sheep
分子量: 26 kDa; 26kD(Calculated).
ユニプロット: Q9BWG6
RRID: AB_2843122

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat,Monkey
予測:
Bovine(100%), Horse(100%), Sheep(100%)
クローナリティ:
Polyclonal
特異性:
SCNM1 Antibody detects endogenous levels of total SCNM1.
RRID:
AB_2843122
引用形式: Affinity Biosciences Cat# DF9928, RRID:AB_2843122.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

SCNM 1; Sodium channel modifier 1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSFKREGDDWSQLNVLKKRRVGDLLASYIPEDEALMLRDGRFACAICPHRPVLDTLAMLTAHRAGKKHLSSLQLFYGKKQPGKERKQNPKHQNELRREETKAEAPLLTQTRLITQSALHRAPHYNSCCRRKYRPEAPGPSVSLSPMPPSEVKLQSGKISREPEPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLRSSGWIPDGRGRWVKDENVEFDSDEEEPPDLPLD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
75
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BWG6 基板として

Site PTM Type Enzyme
S2 Phosphorylation
K17 Ubiquitination
Y76 Phosphorylation
K101 Ubiquitination
S126 Phosphorylation
S144 Phosphorylation
S159 Phosphorylation
S183 Phosphorylation
Y193 Phosphorylation
T195 Phosphorylation
S219 Phosphorylation

研究背景

機能:

Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.

細胞の位置付け:

Nucleus>Nucleoplasm. Nucleus speckle.
Note: Colocalizes with LUC7L2 and SNRNP70 in nuclear speckles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with spliceosomal Sm proteins. Interacts with LUC7L2 and SNRNP70, which suggests a role as a spliceosome component (By similarity).

Restrictive clause

 

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