SLC9A2 Antibody - #DF9936
| 製品: | SLC9A2 Antibody |
| カタログ: | DF9936 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC9A2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Rabbit, Dog |
| 分子量: | 92 kDa; 92kD(Calculated). |
| ユニプロット: | Q9UBY0 |
| RRID: | AB_2843130 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9936, RRID:AB_2843130.
折りたたみ／展開
H7; Na(+)/H(+) exchanger 2; NHE 2; NHE-2; NHE2; SL9A2_HUMAN; Slc9a2; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 2; Solute carrier family 9 (sodium/hydrogen exchanger), member 2; Solute carrier family 9 member 2; Solute carrier family 9, member 2;
免疫原
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
- Q9UBY0 SL9A2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPLGNWRSLRAPLPPMLLLLLLQVAGPVGALAETLLNAPRAMGTSSSPPSPASVVAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLNDCREEKIRKVTSSETDEIRELLSRNLYQIRQRTLSYNRHSLTADTSERQAKEILIRRRHSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAGTTVLNLQPRARRFLPEQFSKKSPQSYKMEWKNEVDVDSGRDMPSTPPTPHSREKGTQTSGLLQQPLLSKDQSGSEREDSLTEGIPPKPPPRLVWRASEPGSRKARFGSEKP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UBY0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y356 | Phosphorylation | Uniprot | |
| Y361 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| Y503 | Phosphorylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| S551 | Phosphorylation | Uniprot | |
| Y610 | Phosphorylation | Uniprot | |
| S623 | Phosphorylation | Uniprot | |
| S643 | Phosphorylation | Uniprot | |
| S647 | Phosphorylation | Uniprot | |
| S652 | Phosphorylation | Uniprot | |
| S661 | Phosphorylation | Uniprot | |
| T662 | Phosphorylation | Uniprot | |
| S665 | Phosphorylation | Uniprot | |
| Y667 | Phosphorylation | Uniprot | |
| S669 | Phosphorylation | Uniprot | |
| T674 | Phosphorylation | Uniprot | |
| K679 | Acetylation | Uniprot | |
| S739 | Phosphorylation | Uniprot | |
| S745 | Phosphorylation | Uniprot | |
| T746 | Phosphorylation | Uniprot | |
| T749 | Phosphorylation | Uniprot | |
| S752 | Phosphorylation | Uniprot | |
| T757 | Phosphorylation | Uniprot |
研究背景
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Phosphorylated (Possible).
Membrane>Multi-pass membrane protein.
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
Interacts with CHP1 and CHP2.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
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