SFRS9 Antibody - #DF9948
| 製品: | SFRS9 Antibody |
| カタログ: | DF9948 |
| タンパク質の説明: | Rabbit polyclonal antibody to SFRS9 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 26 kDa; 26kD(Calculated). |
| ユニプロット: | Q13242 |
| RRID: | AB_2843142 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9948, RRID:AB_2843142.
折りたたみ／展開
arginine/serine-rich 9; Pre mRNA splicing factor SRp30C; Pre-mRNA-splicing factor SRp30C; Serine/arginine-rich splicing factor 9; SFRS 9; Splicing factor; Splicing factor arginine/serine rich 9; splicing factor, arginine/serine-rich 9; splicing factor, arginine/serine-rich, 30-KD, C; SR splicing factor 9; SRP30C; SRSF9; SRSF9_HUMAN;
免疫原
Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
- Q13242 SRSF9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13242 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| R8 | Methylation | Uniprot | |
| Y17 | Phosphorylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| R63 | Methylation | Uniprot | |
| Y70 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| C80 | S-Nitrosylation | Uniprot | |
| R88 | Methylation | Uniprot | |
| R93 | Methylation | Uniprot | |
| R98 | Methylation | Uniprot | |
| R101 | Methylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| R132 | Methylation | Uniprot | |
| Y139 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| Y152 | Phosphorylation | Uniprot | |
| R154 | Methylation | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| Y160 | Phosphorylation | Uniprot | |
| R163 | Methylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| R171 | Methylation | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| Y179 | Phosphorylation | Uniprot | |
| R181 | Methylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| Y190 | Phosphorylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| R194 | Methylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| R209 | Methylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | P24941 (CDK2) | Uniprot |
| Y221 | Phosphorylation | Uniprot |
研究背景
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Extensively phosphorylated on serine residues in the RS domain.
Nucleus.
Note: Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
Interacts with KHDRBS3 (By similarity). Interacts with HABP4. Interacts with NOL3/ARC/NOP30. Interacts with NSEP1/YB-1/YB1. Interacts with SAFB/SAFB1. Interacts with SRSF6/SFRS6. Interacts with TRA2B/SFRS10. Interacts with C1QBP. May also interact with DUSP11/PIR1.
Belongs to the splicing factor SR family.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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