製品: Cables2 Antibody
カタログ: AF9029
タンパク質の説明: Rabbit polyclonal antibody to Cables2
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Dog, Xenopus
分子量: 60kDa; 52kD(Calculated).
ユニプロット: Q9BTV7
RRID: AB_2843220

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(80%), Dog(82%), Xenopus(83%)
クローナリティ:
Polyclonal
特異性:
Cables2 Antibody detects endogenous levels of total Cables2.
RRID:
AB_2843220
引用形式: Affinity Biosciences Cat# AF9029, RRID:AB_2843220.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

C20orf150; CABLES 2; Cdk5 and Abl enzyme substrate 2; CDK5 and ABL1 enzyme substrate 2; dJ908M14.2; Ik3 2; Interactor with CDK3 2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAAAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQVPTGLGLDGQRQRKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTHKSDSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGDTLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLSKIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Xenopus
83
Dog
82
Pig
80
Bovine
71
Sheep
71
Chicken
71
Horse
57
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BTV7 基板として

Site PTM Type Enzyme
T97 Phosphorylation
S105 Phosphorylation
T107 Phosphorylation
S126 Phosphorylation
S130 Phosphorylation
S150 Phosphorylation
S208 Phosphorylation
S259 Phosphorylation
T265 Phosphorylation
S269 Phosphorylation
Y327 Phosphorylation
Y334 Phosphorylation
K361 Ubiquitination

研究背景

機能:

Unknown. Probably involved in G1-S cell cycle transition.

サブユニット構造:

Binds to CDK3, CDK5 and ABL1. The C-terminal cyclin-box-like region binds to CDK5 (By similarity).

タンパク質ファミリー:

Belongs to the cyclin family.

Restrictive clause

 

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