製品: GAAP Antibody
カタログ: AF9068
タンパク質の説明: Rabbit polyclonal antibody to GAAP
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Pig, Rabbit, Chicken, Xenopus
分子量: 23kDa; 27kD(Calculated).
ユニプロット: Q9HC24
RRID: AB_2843259

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(92%), Rabbit(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
GAAP Antibody detects endogenous levels of total GAAP.
RRID:
AB_2843259
引用形式: Affinity Biosciences Cat# AF9068, RRID:AB_2843259.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CGI-119; GAAP; Golgi anti apoptotic protein; LFG4; Protein lifeguard 4; Protein S1R; TMBI4_HUMAN; TMBIM4; Transmembrane BAX inhibitor motif-containing protein 4; Z-protein; ZPRO;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Xenopus
100
Chicken
100
Rabbit
100
Pig
92
Dog
75
Horse
0
Bovine
0
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9HC24 基板として

Site PTM Type Enzyme
Y19 Phosphorylation
S80 Phosphorylation

研究背景

機能:

Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.

細胞の位置付け:

Golgi apparatus membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with ITPR3.

タンパク質ファミリー:

Belongs to the BI1 family. LFG subfamily.

Restrictive clause

 

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For Research Use Only.
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