GPR50 Antibody - #AF9076

(1)  
製品: GPR50 Antibody
カタログ: AF9076
タンパク質の説明: Rabbit polyclonal antibody to GPR50
アプリケーション: WB
反応性: Human
分子量: 68kDa; 67kD(Calculated).
ユニプロット: Q13585
RRID: AB_2843267

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MS Report
HPLC Report
MSDS
説明書
COA
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WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
GPR50 Antibody detects endogenous levels of total GPR50.
RRID:
AB_2843267
引用形式: Affinity Biosciences Cat# AF9076, RRID:AB_2843267.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

G protein coupled receptor 50; G protein-coupled receptor 50; GPR 50; Gpr50; H9; Mel1c; Melatonin-related receptor; MGC125342; MTNRL; MTR1L_HUMAN;

免疫原

免疫原:
Uniprot:

Q13585(MTR1L_HUMAN) >>Visit HPA database.

遺伝子(ID):
GPR50(9248)
発現特異性:
Q13585 MTR1L_HUMAN:

Hypothalamus and pituitary.

タンパク質配列:
MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKPVSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVIDVEDDPDEMAV

PTMs - Q13585 基板として

Site PTM Type Enzyme
S415 Phosphorylation
S425 Phosphorylation
S429 Phosphorylation
Y438 Phosphorylation
S443 Phosphorylation

研究背景

機能:

Does not bind melatonin.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Hypothalamus and pituitary.

サブユニット構造:

Homodimer, and heterodimer with MTNR1A and MTNR1B.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

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