Matriptase Antibody - #AF9109
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF9109, RRID:AB_2843299.
折りたたみ／展開
Epithin; HAI; Matriptase; Membrane type serine protease 1; Membrane type serine protease; Membrane-type serine protease 1; MT SP1; MT-SP1; MTSP 1; MTSP1; Prostamin; PRSS 14; PRSS14; Serine protease 14; Serine protease TADG 15; Serine protease TADG-15; Serine protease TADG15; SNC 19; SNC19; ST 14; ST14; ST14_HUMAN; Suppression of tumorigenicity 14 (colon carcinoma matriptase epithin); Suppression of tumorigenicity 14 (colon carcinoma); Suppression of tumorigenicity 14; Suppressor of tumorigenicity 14 protein; Suppressor of tumorigenicity protein 14; TADG 15; TADG15; TMPRSS14; Tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein;
免疫原
- Q9Y5Y6 ST14_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSDRARKGGGGPKDFGAGLKYNSRHEKVNGLEEGVEFLPVNNVKKVEKHGPGRWVVLAAVLIGLLLVLLGIGFLVWHLQYRDVRVQKVFNGYMRITNENFVDAYENSNSTEFVSLASKVKDALKLLYSGVPFLGPYHKESAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVMLPPRARSLKSFVVTSVVAFPTDSKTVQRTQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEINGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKENTGV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y5Y6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K14 | Ubiquitination | Uniprot | |
| K21 | Methylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| T209 | O-Glycosylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| S338 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| K536 | Acetylation | Uniprot | |
| S554 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S594 | Phosphorylation | Uniprot | |
| S597 | Phosphorylation | Uniprot |
研究背景
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
Membrane>Single-pass type II membrane protein.
Interacts with CDCP1. May interact with TMEFF1.
Belongs to the peptidase S1 family.
研究領域
· Human Diseases > Cancers: Overview > MicroRNAs in cancer.
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