PIG3 Antibody - #AF9159
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF9159, RRID:AB_2843349.
折りたたみ／展開
p53 induced gene 3 protein; p53-induced gene 3 protein; Putative quinone oxidoreductase; QORX_HUMAN; quinone oxidoreductase homolog; Quinone oxidoreductase PIG3; TP53I3; Tumor protein p53 inducible protein 3; Tumor protein p53-inducible protein 3;
免疫原
- Q53FA7 QORX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q53FA7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T85 | Phosphorylation | Uniprot | |
| T100 | Phosphorylation | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| S260 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| K321 | Acetylation | Uniprot |
研究背景
May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).
Homodimer.
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
研究領域
· Cellular Processes > Cell growth and death > p53 signaling pathway. (View pathway)
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