Septin 1 Antibody - #AF9196
| 製品: | Septin 1 Antibody |
| カタログ: | AF9196 |
| タンパク質の説明: | Rabbit polyclonal antibody to Septin 1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit |
| 分子量: | 41kDa; 42kD(Calculated). |
| ユニプロット: | Q8WYJ6 |
| RRID: | AB_2843386 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF9196, RRID:AB_2843386.
折りたたみ／展開
DIFF6; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); LARP; MGC20394; Peanut like protein 3; Peanut-like protein 3; PNUTL3; SEP1; SEPT1; SEPT1_HUMAN; Septin 1; Septin-1; Serologically defined breast cancer antigen NY BR 24; Serologically defined breast cancer antigen NY-BR-24;
免疫原
- Q8WYJ6 SEPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQSDAL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WYJ6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Ubiquitination | Uniprot | |
| Y5 | Phosphorylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| K22 | Ubiquitination | Uniprot | |
| T48 | Phosphorylation | Uniprot | |
| Y51 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| K171 | Ubiquitination | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| Y199 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| R240 | Methylation | Uniprot | |
| Y247 | Phosphorylation | Uniprot | |
| S248 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| T251 | Phosphorylation | Uniprot | |
| K278 | Ubiquitination | Uniprot | |
| Y286 | Phosphorylation | Uniprot | |
| Y289 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| S315 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| T317 | Phosphorylation | Uniprot | |
| K331 | Ubiquitination | Uniprot | |
| K336 | Ubiquitination | Uniprot | |
| K349 | Ubiquitination | Uniprot |
研究背景
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Cytoplasm. Cytoplasm>Cytoskeleton. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Midbody.
Note: Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
Expressed at high levels in lymphoid and hematopoietic tissues.
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with AURKB.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
研究領域
· Human Diseases > Infectious diseases: Bacterial > Bacterial invasion of epithelial cells.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.