WBSCR11 Antibody - #AF9231
| 製品: | WBSCR11 Antibody |
| カタログ: | AF9231 |
| タンパク質の説明: | Rabbit polyclonal antibody to WBSCR11 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 106kDa; 106kD(Calculated). |
| ユニプロット: | Q9UHL9 |
| RRID: | AB_2843421 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF9231, RRID:AB_2843421.
折りたたみ／展開
CREAM1; General transcription factor II I repeat domain containing protein 1; General transcription factor II-I repeat domain-containing protein 1; General transcription factor III; GT2D1_HUMAN; GTF2I repeat domain containing protein 1; GTF2I repeat domain-containing protein 1; GTF2IRD1; GTF3; Muscle TFII I repeat domain-containing protein 1; Muscle TFII-I repeat domain-containing protein 1; MUSTRD1; MusTRD1/BEN; RBAP2; Slow muscle fiber enhancer binding protein; Slow-muscle-fiber enhancer-binding protein; USE B1 binding protein; USE B1-binding protein; WBSCR11; WBSCR12; Williams Beuren syndrome chromosome region 11 protein; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein;
免疫原
Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.
- Q9UHL9 GT2D1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UHL9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K94 | Ubiquitination | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K212 | Sumoylation | Uniprot | |
| K225 | Sumoylation | Uniprot | |
| K271 | Sumoylation | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K308 | Sumoylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| S329 | Phosphorylation | Uniprot | |
| K337 | Sumoylation | Uniprot | |
| K337 | Ubiquitination | Uniprot | |
| K379 | Sumoylation | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K395 | Ubiquitination | Uniprot | |
| T403 | Phosphorylation | Uniprot | |
| Y404 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| K436 | Sumoylation | Uniprot | |
| K436 | Ubiquitination | Uniprot | |
| K443 | Sumoylation | Uniprot | |
| K443 | Ubiquitination | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| T461 | Phosphorylation | Uniprot | |
| S471 | Phosphorylation | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| S477 | Phosphorylation | Uniprot | |
| K495 | Sumoylation | Uniprot | |
| K567 | Sumoylation | Uniprot | |
| Y577 | Phosphorylation | Uniprot | |
| K579 | Sumoylation | Uniprot | |
| K579 | Ubiquitination | Uniprot | |
| S584 | Phosphorylation | Uniprot | |
| K638 | Sumoylation | Uniprot | |
| S654 | Phosphorylation | Uniprot | |
| K684 | Sumoylation | Uniprot | |
| K684 | Ubiquitination | Uniprot | |
| T704 | Phosphorylation | Uniprot | |
| K715 | Ubiquitination | Uniprot | |
| K716 | Ubiquitination | Uniprot | |
| Y717 | Phosphorylation | Uniprot | |
| K724 | Sumoylation | Uniprot | |
| K724 | Ubiquitination | Uniprot | |
| K754 | Ubiquitination | Uniprot | |
| K787 | Sumoylation | Uniprot | |
| K799 | Ubiquitination | Uniprot | |
| K807 | Ubiquitination | Uniprot | |
| Y814 | Phosphorylation | Uniprot | |
| Y828 | Phosphorylation | Uniprot | |
| K829 | Sumoylation | Uniprot | |
| K829 | Ubiquitination | Uniprot | |
| S834 | Phosphorylation | Uniprot | |
| S906 | Phosphorylation | Uniprot | |
| S914 | Phosphorylation | Uniprot | |
| S915 | Phosphorylation | Uniprot | |
| S916 | Phosphorylation | Uniprot | |
| S917 | Phosphorylation | Uniprot |
研究背景
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).
Nucleus.
Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.
Interacts with the retinoblastoma protein (RB1) via its C-terminus.
The N-terminal half may have an activating activity.
Belongs to the TFII-I family.
研究領域
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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