Phospho-CKB (Ser199) Antibody - #AF8602
| 製品: | Phospho-CKB (Ser199) Antibody |
| カタログ: | AF8602 |
| タンパク質の説明: | Rabbit polyclonal antibody to Phospho-CKB (Ser199) |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 43 kDa; 43kD(Calculated). |
| ユニプロット: | P12277 |
| RRID: | AB_2843453 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF8602, RRID:AB_2843453.
折りたたみ／展開
B CK; B-CK; BB-CK; BCK; Brain creatine kinase; Ckb; CKBB; Creatine kinase B; Creatine kinase B chain; Creatine kinase B type; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Creatine kinase brain type; Creatine phosphokinase BB; Epididymis luminal protein 211; Epididymis secretory protein Li 29; HEL 211; HEL S 29; KCRB_HUMAN;
免疫原
- P12277 KCRB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPFSNSHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12277 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| K11 | Ubiquitination | Uniprot | |
| R13 | Methylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| T35 | Phosphorylation | Uniprot | |
| Y39 | Phosphorylation | Uniprot | |
| R43 | Methylation | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| Y82 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| R96 | Methylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| Y125 | Phosphorylation | Uniprot | |
| S128 | Phosphorylation | Uniprot | |
| T133 | Phosphorylation | Uniprot | |
| S136 | Phosphorylation | Uniprot | |
| R138 | Methylation | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| S164 | Phosphorylation | Uniprot | |
| R172 | Methylation | Uniprot | |
| Y173 | Phosphorylation | Uniprot | |
| Y174 | Phosphorylation | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| R215 | Methylation | Uniprot | |
| K223 | Sumoylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| C254 | S-Nitrosylation | Uniprot | |
| T255 | Phosphorylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| K267 | Acetylation | Uniprot | |
| Y269 | Phosphorylation | Uniprot | |
| Y279 | Phosphorylation | Uniprot | |
| S285 | Phosphorylation | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| K307 | Sumoylation | Uniprot | |
| K307 | Ubiquitination | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| K313 | Acetylation | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| R320 | Methylation | Uniprot | |
| T322 | Phosphorylation | Uniprot | |
| T327 | Phosphorylation | Uniprot | |
| S337 | Phosphorylation | Uniprot | |
| K381 | Ubiquitination | Uniprot |
研究背景
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Cytoplasm.
Dimer of identical or non-identical chains, which can be either B (brain type) or M (muscle type). With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
Belongs to the ATP:guanido phosphotransferase family.
研究領域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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