製品: Phospho-FABP7 (Thr117) Antibody
カタログ: AF7034
タンパク質の説明: Rabbit polyclonal antibody to Phospho-FABP7 (Thr117)
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
分子量: 15kDa; 15kD(Calculated).
ユニプロット: O15540
RRID: AB_2843474

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(88%), Horse(88%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(88%)
クローナリティ:
Polyclonal
特異性:
Phospho-FABP7 (Thr117) Antibody detects endogenous levels of FABP7 only when phosphorylated at Thr117.
RRID:
AB_2843474
引用形式: Affinity Biosciences Cat# AF7034, RRID:AB_2843474.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B FABP; B-FABP; BFABP; BLBP; Brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABP7_HUMAN; FABPB; Fatty Acid Binding Protein 7; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; Mammary derived growth inhibitor related; Mammary-derived growth inhibitor related; MRG; OTTHUMP00000017119;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O15540 FABP7_HUMAN:

Expressed in brain and other neural tissues.

タンパク質配列:
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Sheep
100
Dog
100
Chicken
100
Horse
88
Bovine
88
Xenopus
88
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O15540 基板として

Site PTM Type Enzyme
T54 Phosphorylation
T57 Phosphorylation
T61 Phosphorylation
T117 Phosphorylation
T119 Phosphorylation
Y129 Phosphorylation

研究背景

機能:

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in brain and other neural tissues.

タンパク質ファミリー:

Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

研究領域

· Organismal Systems > Endocrine system > PPAR signaling pathway.

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