Phospho-HPRT1 (Ser110) Antibody - #AF7067
| 製品: | Phospho-HPRT1 (Ser110) Antibody |
| カタログ: | AF7067 |
| タンパク質の説明: | Rabbit polyclonal antibody to Phospho-HPRT1 (Ser110) |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus |
| 分子量: | 25kDa; 25kD(Calculated). |
| ユニプロット: | P00492 |
| RRID: | AB_2843507 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF7067, RRID:AB_2843507.
折りたたみ／展開
HGPRT; HGPRTase; HPRT 1; HPRT_HUMAN; HPRT1; Hypoxanthine guanine phosphoribosyltransferase; Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome); Hypoxanthine phosphoribosyltransferase 1; Hypoxanthine-guanine phosphoribosyltransferase;
免疫原
- P00492 HPRT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00492 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| T96 | Phosphorylation | Uniprot | |
| K103 | Methylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| C106 | S-Nitrosylation | Uniprot | |
| S110 | Phosphorylation | Uniprot | |
| K115 | Acetylation | Uniprot | |
| K115 | Sumoylation | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| T124 | Phosphorylation | Uniprot | |
| T126 | Phosphorylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| T139 | Phosphorylation | Uniprot | |
| T142 | Phosphorylation | Uniprot | |
| T145 | Phosphorylation | Uniprot | |
| S148 | Phosphorylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| Y198 | Phosphorylation | Uniprot | |
| K213 | Ubiquitination | Uniprot |
研究背景
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
Cytoplasm.
Homotetramer.
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
研究領域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
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