Phospho-KIF20A (Tyr869) Antibody - #AF7164
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF7164, RRID:AB_2843604.
折りたたみ／展開
AA415432; FLJ21151; GG10 2; GG10_2; KI20A_HUMAN; KIF20A; kinesin family member 20A; Kinesin like protein KIF20A; Kinesin-like protein 174; Kinesin-like protein KIF20A; mitotic kinesin like protein 2; Mitotic kinesin-like protein 2; MKlp2; OTTHUMP00000159481; RAB6 interacting, kinesin like (rabkinesin6); Rab6-interacting kinesin-like protein; RAB6-INTERACTING PROTEIN, KINESIN-LIKE; RAB6KIFL; Rabkinesin 6; Rabkinesin-6;
免疫原
- O95235 KI20A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95235 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| T198 | Phosphorylation | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| S240 | Phosphorylation | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| S244 | Phosphorylation | Uniprot | |
| Y246 | Phosphorylation | Uniprot | |
| S249 | Phosphorylation | Uniprot | |
| T255 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| S274 | Phosphorylation | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K357 | Ubiquitination | Uniprot | |
| K364 | Ubiquitination | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| K425 | Ubiquitination | Uniprot | |
| K453 | Ubiquitination | Uniprot | |
| S522 | Phosphorylation | Uniprot | |
| S528 | Phosphorylation | Uniprot | |
| S532 | Phosphorylation | Uniprot | |
| K537 | Ubiquitination | Uniprot | |
| K540 | Ubiquitination | Uniprot | |
| T543 | Phosphorylation | Uniprot | |
| S556 | Phosphorylation | Uniprot | |
| Y558 | Phosphorylation | Uniprot | |
| T572 | Phosphorylation | Uniprot | |
| K576 | Ubiquitination | Uniprot | |
| K581 | Ubiquitination | Uniprot | |
| K625 | Ubiquitination | Uniprot | |
| K630 | Ubiquitination | Uniprot | |
| S632 | Phosphorylation | Uniprot | |
| S635 | Phosphorylation | Uniprot | |
| Y637 | Phosphorylation | Uniprot | |
| K647 | Ubiquitination | Uniprot | |
| S662 | Phosphorylation | Uniprot | |
| S668 | Phosphorylation | Uniprot | |
| S670 | Phosphorylation | Uniprot | |
| S677 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| S685 | Phosphorylation | Uniprot | |
| T686 | Phosphorylation | Uniprot | |
| K693 | Ubiquitination | Uniprot | |
| S705 | Phosphorylation | Uniprot | |
| T706 | Phosphorylation | Uniprot | |
| K712 | Ubiquitination | Uniprot | |
| K739 | Ubiquitination | Uniprot | |
| K750 | Ubiquitination | Uniprot | |
| S754 | Phosphorylation | Uniprot | |
| S757 | Phosphorylation | Uniprot | |
| K819 | Ubiquitination | Uniprot | |
| S825 | Phosphorylation | Uniprot | |
| K827 | Ubiquitination | Uniprot | |
| T832 | Phosphorylation | Uniprot | |
| T857 | Phosphorylation | Uniprot | |
| T859 | Phosphorylation | Uniprot | |
| S862 | Phosphorylation | Uniprot | |
| S863 | Phosphorylation | Uniprot | |
| T864 | Phosphorylation | Uniprot | |
| S867 | Phosphorylation | Uniprot | |
| Y869 | Phosphorylation | Uniprot | |
| S875 | Phosphorylation | Uniprot | |
| S878 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| S883 | Phosphorylation | Uniprot |
研究背景
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle.
Golgi apparatus. Cytoplasm>Cytoskeleton>Spindle.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.