Phospho-LDHA (Tyr239) Antibody - #AF7173
(1)
(7)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF7173, RRID:AB_2843613.
折りたたみ／展開
Cell proliferation-inducing gene 19 protein; L lactate dehydrogenase A chain; Lactate dehydrogenase A; LDH A; LDH M; LDH muscle subunit; LDH1; LDH5; LDHA; PIG 19; PIG19; Renal carcinoma antigen NY-REN-59;
免疫原
- P00338 LDHA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00338 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| K5 | Acetylation | Uniprot | |
| K5 | Methylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| Y10 | Phosphorylation | P11362 (FGFR1) , P04626 (ERBB2) , P12931 (SRC) | Uniprot |
| K14 | Acetylation | Uniprot | |
| K14 | Sumoylation | Uniprot | |
| K14 | Ubiquitination | Uniprot | |
| T18 | Phosphorylation | Uniprot | |
| K22 | Acetylation | Uniprot | |
| K57 | Acetylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| T74 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| Y83 | Phosphorylation | P11362 (FGFR1) | Uniprot |
| S89 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K118 | Acetylation | Uniprot | |
| K118 | Methylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| K126 | Acetylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| Y127 | Phosphorylation | Uniprot | |
| S128 | Phosphorylation | Uniprot | |
| K132 | Acetylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| R157 | Methylation | Uniprot | |
| S161 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| R169 | Methylation | Uniprot | |
| Y172 | Phosphorylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K222 | Acetylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K224 | Acetylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K228 | Acetylation | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K232 | Acetylation | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| Y239 | Phosphorylation | Uniprot | |
| K243 | Acetylation | Uniprot | |
| K243 | Ubiquitination | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| T248 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S249 | Phosphorylation | Uniprot | |
| R269 | Methylation | Uniprot | |
| K278 | Acetylation | Uniprot | |
| K278 | Methylation | Uniprot | |
| K278 | Ubiquitination | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| S310 | Phosphorylation | Uniprot | |
| K317 | Ubiquitination | Uniprot | |
| K318 | Acetylation | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| T322 | Phosphorylation | Uniprot | |
| K328 | Acetylation | Uniprot | |
| K328 | Sumoylation | Uniprot | |
| K328 | Ubiquitination | Uniprot |
研究背景
ISGylated.
Cytoplasm.
Homotetramer.
Belongs to the LDH/MDH superfamily. LDH family.
研究領域
· Environmental Information Processing > Signal transduction > HIF-1 signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer. (View pathway)
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Carbohydrate metabolism > Propanoate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Endocrine system > Glucagon signaling pathway.
参考文献
Application: WB Species: Mouse Sample: macrophages
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.