製品: Phospho-TCTP (Ser53) Antibody
カタログ: AF7222
タンパク質の説明: Rabbit polyclonal antibody to Phospho-TCTP (Ser53)
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
分子量: 24KD; 20kD(Calculated).
ユニプロット: P13693
RRID: AB_2843662

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(80%)
クローナリティ:
Polyclonal
特異性:
Phospho-TCTP (Ser53) Antibody detects endogenous levels of TCTP only when phosphorylated at Ser53.
RRID:
AB_2843662
引用形式: Affinity Biosciences Cat# AF7222, RRID:AB_2843662.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ27337; Fortilin; Histamine releasing factor; Histamine-releasing factor; HRF; Immunoglobulin E-dependent; p02; p23; TCTP; TCTP_HUMAN; tpt1; Translationally controlled tumor protein; Translationally-controlled tumor protein; Tumor protein translationally controlled 1; tumor protein, translationally-controlled 1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P13693 TCTP_HUMAN:

Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.

タンパク質配列:
MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Zebrafish
100
Chicken
100
Rabbit
100
Xenopus
80
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P13693 基板として

Site PTM Type Enzyme
S9 Phosphorylation
S15 Phosphorylation
Y18 Phosphorylation
K19 Acetylation
K19 Ubiquitination
S37 Phosphorylation
T39 Phosphorylation
S46 Phosphorylation P53350 (PLK1)
S53 Phosphorylation
S64 Phosphorylation P53350 (PLK1)
T65 Phosphorylation
Y88 Phosphorylation
Y91 Phosphorylation
K93 Acetylation
K93 Ubiquitination
Y95 Phosphorylation
K97 Acetylation
K97 Ubiquitination
S98 Phosphorylation
K102 Acetylation
K102 Sumoylation
K102 Ubiquitination
K112 Acetylation
K112 Sumoylation
K112 Ubiquitination
T116 Phosphorylation
K123 Ubiquitination
K130 Methylation
K130 Sumoylation
Y159 Phosphorylation
K164 Ubiquitination
K171 Ubiquitination

研究背景

機能:

Involved in calcium binding and microtubule stabilization.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.

サブユニット構造:

Interacts with STEAP3.

タンパク質ファミリー:

Belongs to the TCTP family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.