製品: Gz alpha Antibody
カタログ: AF0091
タンパク質の説明: Rabbit polyclonal antibody to Gz alpha
アプリケーション: WB IHC
反応性: Human, Mouse, Rat, Monkey
予測: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
分子量: 41kDa; 41kD(Calculated).
ユニプロット: P19086
RRID: AB_2833274

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat,Monkey
予測:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
Gz alpha Antibody detects endogenous levels of total Gz alpha.
RRID:
AB_2833274
引用形式: Affinity Biosciences Cat# AF0091, RRID:AB_2833274.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

G(x) alpha chain; GNAZ; GNAZ_HUMAN; Guanine nucleotide binding protein (G protein) alpha z polypeptide; Guanine nucleotide binding protein G(z) alpha subunit G(x) alpha chain; Guanine nucleotide binding protein G(z) subunit alpha; Guanine nucleotide-binding protein G(z) subunit alpha; Gz alpha; Gz-alpha; Human Gx alpha gene; Transducin alpha;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
G-alpha(z) Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily. Note: This description may include information from UniProtKB.
タンパク質配列:
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P19086 基板として

Site PTM Type Enzyme
S16 Phosphorylation Q05655 (PRKCD) , Q13153 (PAK1) , P17252 (PRKCA)
S27 Phosphorylation P17252 (PRKCA) , Q05655 (PRKCD)
T41 Phosphorylation
K51 Ubiquitination
S142 Phosphorylation
K189 Ubiquitination
S229 Phosphorylation
Y231 Phosphorylation
T263 Phosphorylation
S264 Phosphorylation
T341 Phosphorylation

研究背景

機能:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

細胞の位置付け:

Membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

G-proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with ADGRB2.

タンパク質ファミリー:

Belongs to the G-alpha family. G(i/o/t/z) subfamily.

研究領域

· Organismal Systems > Nervous system > Long-term depression.

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