Coagulation Factor III Antibody - #AF7723
製品: | Coagulation Factor III Antibody |
カタログ: | AF7723 |
タンパク質の説明: | Rabbit polyclonal antibody to Coagulation Factor III |
アプリケーション: | WB IF/ICC |
反応性: | Human, Mouse |
予測: | Pig, Bovine, Sheep |
分子量: | 33kDa, 50 kDa; 33kD(Calculated). |
ユニプロット: | P13726 |
RRID: | AB_2844087 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF7723, RRID:AB_2844087.
折りたたみ/展開
CD142; CD142 antigen; Coagulation factor III (thromboplastin tissue factor); Coagulation factor III; F3; FLJ17960; TF; TF_HUMAN; TFA; Thromboplastin; Tissue factor;
免疫原
- P13726 TF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P13726 基板として
研究背景
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Membrane>Single-pass type I membrane protein.
Secreted.
Lung, placenta and pancreas.
Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.
Belongs to the tissue factor family.
研究領域
· Organismal Systems > Immune system > Complement and coagulation cascades. (View pathway)
参考文献
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