Phospho-PPIG (Ser376) Antibody - #AF4466
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF4466, RRID:AB_2844523.
折りたたみ／展開
CARS cyclophilin; CARS Cyp; CARS-cyclophilin; CARS-Cyp; CASP 10; CASP10; Clk associating RS cyclophilin; Clk-associating RS-cyclophilin; Cyclophilin G; CyclophilinG; CYP; MGC133241; Peptidyl prolyl cis trans isomerase G; Peptidyl prolyl isomerase G (cyclophilin G); Peptidyl prolyl isomerase G; Peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; Peptidylprolyl isomerase G (cyclophilin G); Peptidylprolyl isomerase G; PPIase G; Ppig; PPIG_HUMAN; Rotamase G; RotamaseG; SCAF10; SR cyclophilin; SR cyp; SR related CTD associated factor 10; SR-cyclophilin; SR-cyp; SRcyp;
免疫原
- Q13427 PPIG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13427 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K158 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| S196 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S219 | Phosphorylation | Uniprot | |
| T223 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| Y320 | Phosphorylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| S375 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| S386 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| T407 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| S442 | Phosphorylation | Uniprot | |
| K447 | Acetylation | Uniprot | |
| K449 | Acetylation | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| S487 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| S527 | Phosphorylation | Uniprot | |
| S544 | Phosphorylation | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| T552 | Phosphorylation | Uniprot | |
| Y558 | Phosphorylation | Uniprot | |
| S560 | Phosphorylation | Uniprot | |
| S566 | Phosphorylation | Uniprot | |
| S568 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot | |
| S587 | Phosphorylation | Uniprot | |
| T611 | Phosphorylation | Uniprot | |
| S628 | Phosphorylation | Uniprot | |
| S630 | Phosphorylation | Uniprot | |
| S631 | Phosphorylation | Uniprot | |
| S638 | Phosphorylation | Uniprot | |
| S666 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S674 | Phosphorylation | Uniprot | |
| S677 | Phosphorylation | Uniprot | |
| S687 | Phosphorylation | Uniprot | |
| S690 | Phosphorylation | Uniprot | |
| S696 | Phosphorylation | Uniprot | |
| S716 | Phosphorylation | Uniprot | |
| S717 | Phosphorylation | Uniprot | |
| K720 | Acetylation | Uniprot | |
| K724 | Acetylation | Uniprot | |
| S744 | Phosphorylation | Uniprot | |
| S745 | Phosphorylation | Uniprot | |
| T748 | Phosphorylation | Uniprot | |
| S753 | Phosphorylation | Uniprot |
研究背景
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.
Nucleus matrix. Nucleus speckle.
Note: Colocalizes with RNA splicing factors at nuclear speckles.
Ubiquitous.
Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.
The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.
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