SEC5/EXOC2 Antibody - #DF12043
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12043, RRID:AB_2844848.
折りたたみ／展開
EXOC2; EXOC2_HUMAN; Exocyst complex component 2; Exocyst complex component Sec5; FLJ11026; SEC5; SEC5 like 1; SEC5L1; Sec5p;
免疫原
- Q96KP1 EXOC2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96KP1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K71 | Ubiquitination | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| R83 | Methylation | Uniprot | |
| S89 | Phosphorylation | Uniprot | |
| Y113 | Phosphorylation | Uniprot | |
| K122 | Ubiquitination | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| K233 | Ubiquitination | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| S250 | Phosphorylation | Uniprot | |
| T252 | Phosphorylation | Uniprot | |
| T255 | Phosphorylation | Uniprot | |
| K281 | Ubiquitination | Uniprot | |
| K296 | Ubiquitination | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| K315 | Ubiquitination | Uniprot | |
| K322 | Ubiquitination | Uniprot | |
| K323 | Ubiquitination | Uniprot | |
| K342 | Acetylation | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K354 | Ubiquitination | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| Y392 | Phosphorylation | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| S404 | Phosphorylation | Uniprot | |
| T424 | Phosphorylation | Uniprot | |
| S426 | Phosphorylation | Uniprot | |
| K428 | Ubiquitination | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | Uniprot | |
| T440 | Phosphorylation | Uniprot | |
| K454 | Acetylation | Uniprot | |
| K454 | Ubiquitination | Uniprot | |
| K503 | Ubiquitination | Uniprot | |
| K504 | Ubiquitination | Uniprot | |
| S512 | Phosphorylation | Uniprot | |
| K515 | Ubiquitination | Uniprot | |
| K532 | Ubiquitination | Uniprot | |
| Y534 | Phosphorylation | Uniprot | |
| K639 | Ubiquitination | Uniprot | |
| K743 | Ubiquitination | Uniprot | |
| K753 | Ubiquitination | Uniprot | |
| K848 | Ubiquitination | Uniprot | |
| K874 | Ubiquitination | Uniprot | |
| K878 | Ubiquitination | Uniprot | |
| S888 | Phosphorylation | Uniprot | |
| K894 | Ubiquitination | Uniprot | |
| K902 | Ubiquitination | Uniprot | |
| T924 | Phosphorylation | Uniprot |
研究背景
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Midbody>Midbody ring.
Note: Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).
Widely expressed with highest levels in brain and placenta.
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with EXOC3L1 (By similarity). Interacts with GNEFR/DELGEF; this interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALA and RALB.
Interacts with RALA through the TIG domain.
Belongs to the SEC5 family.
研究領域
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
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