Transgelin 2 Antibody - #DF12053
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| 製品: | Transgelin 2 Antibody |
| カタログ: | DF12053 |
| タンパク質の説明: | Rabbit polyclonal antibody to Transgelin 2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 22 kDa; 22kD(Calculated). |
| ユニプロット: | P37802 |
| RRID: | AB_2844858 |
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(82%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
Transgelin 2 Antibody detects endogenous levels of total Transgelin 2.
RRID:
AB_2844858
引用形式: Affinity Biosciences Cat# DF12053, RRID:AB_2844858.
引用形式: Affinity Biosciences Cat# DF12053, RRID:AB_2844858.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
CDABP0035; epididymis tissue protein Li 7e; HA1756; KIAA0120; SM22-alpha homolog; TAGL2_HUMAN; Tagln2; Transgelin-2;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質配列:
- P37802 TAGL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Zebrafish
82
Xenopus
75
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P37802 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| R4 | Methylation | Uniprot | |
| Y8 | Phosphorylation | Uniprot | |
| S11 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| K17 | Acetylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K20 | Acetylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K57 | Sumoylation | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| K78 | Acetylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K79 | Sumoylation | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| S83 | Phosphorylation | O94921 (CDK14) | Uniprot |
| T84 | Phosphorylation | Uniprot | |
| K88 | Acetylation | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T128 | Phosphorylation | Uniprot | |
| R139 | Methylation | Uniprot | |
| S145 | Phosphorylation | Uniprot | |
| K153 | Acetylation | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| S163 | Phosphorylation | O94921 (CDK14) , P17612 (PRKACA) | Uniprot |
| K171 | Acetylation | Uniprot | |
| K171 | Sumoylation | Uniprot | |
| K171 | Ubiquitination | Uniprot | |
| T180 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| R182 | Methylation | Uniprot | |
| S185 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| T190 | Phosphorylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| R196 | Methylation | Uniprot |
研究背景
組織特異性:
Expressed in epididymis (at protein level).
タンパク質ファミリー:
Belongs to the calponin family.
参考文献
1). Comparative proteomics identify HSP90A, STIP1 and TAGLN‑2 in serum extracellular vesicles as potential circulating biomarkers for human adenomyosis. Experimental and Therapeutic Medicine, 2022
(PubMed: 35495589)
[IF=2.7]
Application: WB Species: human Sample: T‑AMEVs and B‑AMEVs
Figure 4. | HSP90A, STIP1 and TAGLN‑2 are expressed in B‑AMEVs and T‑AMEVs. (D and E) HSP90A, STIP1 and TAGLN‑2 were present in T‑AMEVs and B‑AMEVs from patients with adenomyosis,but not in those of patients in the control group.
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