Choline kinase alpha Antibody - #DF12067
| 製品: | Choline kinase alpha Antibody |
| カタログ: | DF12067 |
| タンパク質の説明: | Rabbit polyclonal antibody to Choline kinase alpha |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 50 kDa,52 kDa; 52kD(Calculated). |
| ユニプロット: | P35790 |
| RRID: | AB_2844872 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12067, RRID:AB_2844872.
折りたたみ／展開
CHETK alpha; CHETK-alpha; CHK; CHKA; CK; CKI; EK; Ethanolamine kinase; Choline kinase alpha;
免疫原
- P35790 CHKA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35790 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K96 | Ubiquitination | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| Y197 | Phosphorylation | P12931 (SRC) | Uniprot |
| K247 | Acetylation | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K272 | Ubiquitination | Uniprot | |
| Y333 | Phosphorylation | P12931 (SRC) | Uniprot |
| T371 | Phosphorylation | Uniprot | |
| K373 | Ubiquitination | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| Y437 | Phosphorylation | Uniprot | |
| Y440 | Phosphorylation | Uniprot |
研究背景
Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Cytoplasm.
Heterodimer with CHKB (By similarity). Homodimer.
Belongs to the choline/ethanolamine kinase family.
研究領域
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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