DHRS3 Antibody - #DF12070
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12070, RRID:AB_2844875.
折りたたみ／展開
DD83.1; Dehydrogenase/reductase (SDR family) member 3; DHRS3; DHRS3_HUMAN; EC 1.1.1.300; MGC125166; RDH17; Retinal short chain dehydrogenase/reductase 1; Retinal short-chain dehydrogenase/reductase 1; retSDR1; Rsdr1; SDR family, member 3; SDR1; SDR16C1; Short-chain dehydrogenase/reductase 3; Short-chain dehydrogenase/reductase family, member 3;
免疫原
Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.
- O75911 DHRS3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKGRT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75911 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K32 | Ubiquitination | Uniprot | |
| R48 | Methylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot |
研究背景
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Membrane>Multi-pass membrane protein.
Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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