LGALS3BP Antibody - #DF12079
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製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12079, RRID:AB_2844884.
折りたたみ／展開
90K; 90K MAC 2 BP; Basement membrane autoantigen p105; BTBD17B; Galectin 3 binding protein; Galectin-3-binding protein; L3 antigen; Lectin galactoside binding soluble 3 binding protein; Lectin galactoside-binding soluble 3-binding protein; LG3BP_HUMAN; LGALS3BP; M2BP; Mac 2 binding protein; Mac 2 BP; Mac-2 BP; Mac-2-binding protein; Mac2 BP; MAC2BP; Serum protein 90K; TANGO10B; Transport and golgi organization 10 homolog B; Tumor associated antigen 90K; Tumor-associated antigen 90K;
免疫原
Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
- Q08380 LG3BP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q08380 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y41 | Phosphorylation | Uniprot | |
| N69 | N-Glycosylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| N125 | N-Glycosylation | Uniprot | |
| N192 | N-Glycosylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| N398 | N-Glycosylation | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| T413 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| K427 | Ubiquitination | Uniprot | |
| S428 | Phosphorylation | Uniprot | |
| Y432 | Phosphorylation | Uniprot | |
| S434 | Phosphorylation | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S444 | O-Glycosylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| Y446 | Phosphorylation | Uniprot | |
| Y458 | Phosphorylation | Uniprot | |
| T463 | Phosphorylation | Uniprot | |
| K474 | Ubiquitination | Uniprot | |
| N551 | N-Glycosylation | Uniprot | |
| K554 | Ubiquitination | Uniprot | |
| N580 | N-Glycosylation | Uniprot |
研究背景
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
Secreted. Secreted>Extracellular space>Extracellular matrix.
Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
Homodimers and homomultimers. The multimers form ring-like structures with a diameter of 30-40 nm. Binds LGALS1 and LGALS3. Binds ITGB1, COL4A1, COL5A1, COL6A1, FN1 and NID. Interacts with the gamma-tubulin ring complex (gamma-TuRC), composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. The unglycosylated form interacts with PDE4DIP isoform 13/MMG8/SMYLE; this interaction may connect a pericentrosomal complex, made of AKAP9, CDK5RAP2, EB1/MAPRE1 and PDE4DIP, to the gamma-tubulin ring complex (gamma-TuRC) to promote microtubule assembly and acetylation.
参考文献
Application: WB Species: human Sample: Jurkat cells
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