ERp72 Antibody - #DF12114
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12114, RRID:AB_2844919.
折りたたみ／展開
Calcium binding protein intestinal related; Endoplasmic reticulum resident protein 70; Endoplasmic reticulum resident protein 72; EPR70; EPR72; ER protein 70; ER protein 72; ERP 70; ERp 72; ERp-72; ERp70; ERp72; PDIA 4; Pdia4; PDIA4_HUMAN; PDIR; Protein disulfide isomerase A4; Protein disulfide isomerase associated 4; Protein disulfide isomerase family A member 4; protein disulfide isomerase related protein (calcium-binding protein, intestinal-related); Protein disulfide isomerase related protein; Protein disulfide-isomerase A4; Protein ERp 72; Protein ERp72;
免疫原
- P13667 PDIA4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRPRKAFLLLLLLGLVQLLAVAGAEGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSAIKDFVLKYALPLVGHRKVSNDAKRYTRRPLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGLSESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P13667 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y101 | Phosphorylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| S124 | Phosphorylation | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| Y137 | Phosphorylation | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| T173 | Phosphorylation | Uniprot | |
| K218 | Ubiquitination | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| T238 | Phosphorylation | Uniprot | |
| T241 | Phosphorylation | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| Y252 | Phosphorylation | Uniprot | |
| T254 | Phosphorylation | Uniprot | |
| K256 | Acetylation | Uniprot | |
| K256 | Ubiquitination | Uniprot | |
| Y266 | Phosphorylation | Uniprot | |
| R270 | Methylation | Uniprot | |
| Y273 | Phosphorylation | Uniprot | |
| Y278 | Phosphorylation | Uniprot | |
| S287 | Phosphorylation | Uniprot | |
| K294 | Ubiquitination | Uniprot | |
| Y320 | Phosphorylation | Uniprot | |
| Y323 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| K366 | Acetylation | Uniprot | |
| Y367 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| T380 | Phosphorylation | Uniprot | |
| S383 | Phosphorylation | Uniprot | |
| K391 | Ubiquitination | Uniprot | |
| Y392 | Phosphorylation | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| Y409 | Phosphorylation | Uniprot | |
| T410 | Phosphorylation | Uniprot | |
| Y448 | Phosphorylation | Uniprot | |
| T449 | Phosphorylation | Uniprot | |
| Y458 | Phosphorylation | Uniprot | |
| S468 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| K484 | Acetylation | Uniprot | |
| K484 | Ubiquitination | Uniprot | |
| K485 | Acetylation | Uniprot | |
| S495 | Phosphorylation | Uniprot | |
| T503 | O-Glycosylation | Uniprot | |
| K506 | Acetylation | Uniprot | |
| K509 | Acetylation | Uniprot | |
| S516 | Phosphorylation | Uniprot | |
| K533 | Acetylation | Uniprot | |
| Y551 | Phosphorylation | Uniprot | |
| Y565 | Phosphorylation | Uniprot | |
| S567 | Phosphorylation | Uniprot | |
| K576 | Ubiquitination | Uniprot | |
| T586 | Phosphorylation | Uniprot | |
| S592 | Phosphorylation | Uniprot | |
| R594 | Methylation | Uniprot | |
| K596 | Acetylation | Uniprot | |
| Y604 | Phosphorylation | Uniprot | |
| S608 | Phosphorylation | Uniprot |
研究背景
Endoplasmic reticulum lumen. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Component of a complex containing at least CRELD2, MANF, MATN3 and PDIA4 (By similarity).
Belongs to the protein disulfide isomerase family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.
· Organismal Systems > Endocrine system > Thyroid hormone synthesis.
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