GNMT Antibody - #DF12117
| 製品: | GNMT Antibody |
| カタログ: | DF12117 |
| タンパク質の説明: | Rabbit polyclonal antibody to GNMT |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 33 kDa; 33kD(Calculated). |
| ユニプロット: | Q14749 |
| RRID: | AB_2844922 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12117, RRID:AB_2844922.
折りたたみ／展開
EC 2.1.1.20; Glycine N methyltransferase; Glycine N-methyltransferase; Gnmt; GNMT_HUMAN; OTTHUMP00000016412;
免疫原
- Q14749 GNMT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14749 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| Y22 | Phosphorylation | Uniprot | |
| Y34 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K97 | Acetylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y197 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T220 | Phosphorylation | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot |
研究背景
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cytoplasm.
Abundant in liver.
Homotetramer.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
研究領域
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
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