Collagen Type VI Antibody - #DF12191
| 製品: | Collagen Type VI Antibody |
| カタログ: | DF12191 |
| タンパク質の説明: | Rabbit polyclonal antibody to Collagen Type VI |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Bovine, Sheep, Dog, Chicken |
| 分子量: | 140 kDa; 109kD(Calculated). |
| ユニプロット: | P12109 |
| RRID: | AB_2844996 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12191, RRID:AB_2844996.
折りたたみ／展開
Alpha 1 (VI) chain (61 AA); CO6A1_HUMAN; COL6A1; Collagen alpha-1(VI) chain; Collagen VI, alpha 1 polypeptide; Collagen, intimal short chain collagen; Collagen, type VI, alpha 1; OPLL; OTTHUMP00000115501;
免疫原
- P12109 CO6A1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQTVSRKVALG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12109 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T104 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| K121 | Acetylation | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| K134 | Acetylation | Uniprot | |
| Y152 | Phosphorylation | Uniprot | |
| T157 | Phosphorylation | Uniprot | |
| Y165 | Phosphorylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| N212 | N-Glycosylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| S348 | Phosphorylation | Uniprot | |
| Y477 | Phosphorylation | Uniprot | |
| S486 | Phosphorylation | Uniprot | |
| N516 | N-Glycosylation | Uniprot | |
| K688 | Ubiquitination | Uniprot | |
| S746 | Phosphorylation | Uniprot | |
| S766 | Phosphorylation | Uniprot | |
| Y793 | Phosphorylation | Uniprot | |
| N804 | N-Glycosylation | Uniprot | |
| Y878 | Phosphorylation | Uniprot | |
| N896 | N-Glycosylation | Uniprot | |
| S1008 | Phosphorylation | Uniprot |
研究背景
Collagen VI acts as a cell-binding protein.
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Secreted>Extracellular space>Extracellular matrix.
Trimers composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI).
Belongs to the type VI collagen family.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Focal adhesion. (View pathway)
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
· Organismal Systems > Digestive system > Protein digestion and absorption.
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