P4HA1 Antibody - #DF12219
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12219, RRID:AB_2845024.
折りたたみ／展開
2-oxoglutarate-4-dioxygenase subunit alpha-1; 4-hydroxylase, alpha I subunit; 4-PH alpha-1; P4HA; P4HA1; P4HA1_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; Prolyl 4-hydroxylase subunit alpha-1;
免疫原
- P13674 P4HA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P13674 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T40 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| Y45 | Phosphorylation | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| N113 | N-Glycosylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| Y282 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K327 | Ubiquitination | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| K353 | Ubiquitination | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| K382 | Acetylation | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| S387 | Phosphorylation | Uniprot | |
| K442 | Ubiquitination | Uniprot | |
| K510 | Ubiquitination | Uniprot | |
| K515 | Ubiquitination | Uniprot |
研究背景
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Endoplasmic reticulum lumen.
Heterotetramer of two alpha-1 chains and two beta chains (the beta chain is the multi-functional PDI).
Belongs to the P4HA family.
研究領域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
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For Research Use Only.
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