TOM40 Antibody - #DF12239
製品: | TOM40 Antibody |
カタログ: | DF12239 |
タンパク質の説明: | Rabbit polyclonal antibody to TOM40 |
アプリケーション: | WB IHC |
反応性: | Human, Mouse, Rat |
予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 38 kDa; 38kD(Calculated). |
ユニプロット: | O96008 |
RRID: | AB_2845044 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12239, RRID:AB_2845044.
折りたたみ/展開
C19orf1; D19S1177E; Haymaker protein; Mitochondrial import receptor subunit TOM40 homolog; Mitochondrial outer membrane protein; Mitochondrial outer membrane protein TOM40; p38.5; PER EC1; PEREC1; Probable mitochondrial import receptor subunit TOM40 homolog; Protein Haymaker; TOM40; TOM40_HUMAN; TOMM40; Translocase of outer membrane 40 kDa subunit homolog; Translocase of outer mitochondrial membrane 40; Translocase of outer mitochondrial membrane 40 homolog (yeast); Translocase of outer mitochondrial membrane 40 homolog; Translocase of outer mitochondrial membrane 40, yeast, homolog of;
免疫原
- O96008 TOM40_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O96008 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S54 | Phosphorylation | Uniprot | |
K91 | Ubiquitination | Uniprot | |
K102 | Ubiquitination | Uniprot | |
Y129 | Phosphorylation | Uniprot | |
S142 | Phosphorylation | Uniprot | |
T144 | Phosphorylation | Uniprot | |
S157 | Phosphorylation | Uniprot | |
K175 | Ubiquitination | Uniprot | |
K184 | Ubiquitination | Uniprot | |
Y194 | Phosphorylation | Uniprot | |
Y254 | Phosphorylation | Uniprot | |
T255 | Phosphorylation | Uniprot | |
T273 | Phosphorylation | Uniprot | |
K309 | Ubiquitination | Uniprot | |
S317 | Phosphorylation | Uniprot | |
S320 | Phosphorylation | Uniprot | |
T338 | Phosphorylation | Uniprot |
研究背景
Channel-forming protein essential for import of protein precursors into mitochondria.
Mitochondrion outer membrane>Multi-pass membrane protein.
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with mitochondrial targeting sequences. Interacts with TIMM29; linking the TIM22 complex to the TOM complex. Interacts (via N-terminus) with CYP1A1 (via mitochondrial targeting signal); this interaction is required for CYP1A1 translocation across the mitochondrial outer membrane.
Belongs to the Tom40 family.
研究領域
· Human Diseases > Neurodegenerative diseases > Amyotrophic lateral sclerosis (ALS).
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