VNN1 Antibody - #DF12241
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12241, RRID:AB_2845046.
折りたたみ／展開
HDLCQ8; High density lipoprotein cholesterol level quantitative trait locus 8, included; Pantetheinase; Pantetheine hydrolase; Tiff66; V-1; Vanin 1; Vanin-1; Vannin 1; Vascular non inflammatory molecule 1; Vascular non-inflammatory molecule 1; VNN 1; VNN1; VNN1_HUMAN;
免疫原
Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.
- O95497 VNN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTQLPAYVAILLFYVSRASCQDTFTAAVYEHAAILPNATLTPVSREEALALMNRNLDILEGAITSAADQGAHIIVTPEDAIYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPVQERLSCLAKNNSIYVVANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGENQFNVPKEPEIVTFNTTFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMNVLPHLSAVEFHSAWAMGMRVNFLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLLLSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQICTLLKCKTTNLNTCGDSAETASTRFEMFSLSGTFGTQYVFPEVLLSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLYEKDWASNASSGLTAQARIIMLIVIAPIVCSLSW
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95497 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N38 | N-Glycosylation | Uniprot | |
| N130 | N-Glycosylation | Uniprot | |
| Y134 | Phosphorylation | Uniprot | |
| T275 | Phosphorylation | Uniprot | |
| N283 | N-Glycosylation | Uniprot | |
| S285 | Phosphorylation | Uniprot | |
| K293 | Acetylation | Uniprot | |
| N315 | N-Glycosylation | Uniprot | |
| N353 | N-Glycosylation | Uniprot |
研究背景
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Cell membrane>Lipid-anchor.
Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.
Monomer.
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.
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