CKMT1A Antibody - #DF12257
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12257, RRID:AB_2845062.
折りたたみ／展開
Acidic-type mitochondrial creatine kinase; CKMT; CKMT1; CKMT1B; Creatine kinase mitochondrial 1 (ubiquitous); Creatine kinase mitochondrial 1B; Creatine kinase U type mitochondrial; Creatine kinase U-type; KCRU_HUMAN; Mia-CK; mitochondrial; U-MtCK; Ubiquitous mitochondrial creatine kinase; UMTCK;
免疫原
- P12532 KCRU_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGPFSRLLSARPGLRLLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12532 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C62 | S-Nitrosylation | Uniprot | |
| T141 | Phosphorylation | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| Y153 | Phosphorylation | Uniprot | |
| R157 | Methylation | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| S196 | Phosphorylation | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| Y312 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| R349 | Methylation | Uniprot | |
| R407 | Methylation | Uniprot | |
| T410 | Phosphorylation | Uniprot |
研究背景
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Mitochondrion inner membrane>Peripheral membrane protein>Intermembrane side.
Exists as an octamer composed of four MTCK homodimers.
Belongs to the ATP:guanido phosphotransferase family.
研究領域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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