FECH Antibody - #DF12273
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12273, RRID:AB_2845078.
折りたたみ／展開
EPP; FCE; Fch; Fcl; fech; Ferrochelatase (protoporphyria); Ferrochelatase; Ferrochelatase mitochondrial; Heme synthase; Heme synthetase; HEMH_HUMAN; mitochondrial; Protoheme ferro lyase; Protoheme ferro-lyase; Protoporphyria;
免疫原
- P22830 HEMH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P22830 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K37 | Acetylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| T315 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| K415 | Acetylation | Uniprot | |
| S420 | Phosphorylation | Uniprot |
研究背景
Catalyzes the ferrous insertion into protoporphyrin IX.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Homodimer.
Belongs to the ferrochelatase family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
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