NDUFB11 Antibody - #DF12300
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12300, RRID:AB_2845105.
折りたたみ／展開
CI ESSS; Complex I ESSS; complex I NP17.3 subunit; ESSS; FLJ20494; MGC111182; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 17.3kDa; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 mitochondrial; NADH ubiquinone oxidoreductase ESSS subunit; NDUFB 11; Neuronal protein 17.3; Np15; NP17.3; P17.3;
免疫原
- Q9NX14 NDUBB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAGLFGLSARRLLAAAATRGLPAARVRWESSFSRTVVAPSAVAGKRPPEPTTPWQEDPEPEDENLYEKNPDSHGYDKDPVLDVWNMRLVFFFGVSIILVLGSTFVAYLPDYRMKEWSRREAERLVKYREANGLPIMESNCFDPSKIQLPEDE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NX14 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R12 | Methylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| T53 | Phosphorylation | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Single-pass membrane protein.
Ubiquitous.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFB11 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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