Pax-5 Antibody - #AF0238
| 製品: | Pax-5 Antibody |
| カタログ: | AF0238 |
| タンパク質の説明: | Rabbit polyclonal antibody to Pax-5 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Horse, Rabbit, Dog |
| 分子量: | 40kDa; 42kD(Calculated). |
| ユニプロット: | Q02548 |
| RRID: | AB_2833413 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0238, RRID:AB_2833413.
折りたたみ／展開
B cell lineage specific activator; B cell lineage specific activator protein; B cell specific activator protein; B cell specific transcription factor; B-cell-specific transcription factor; BSAP; EBB-1; KLP; Paired box 5; Paired box gene 5 (B cell lineage specific activator protein); Paired box gene 5 (B cell lineage specific activator); Paired box gene 5; Paired box homeotic gene 5; Paired box protein Pax 5; Paired box protein Pax-5; Paired domain gene 5; PAX 5; PAX5; PAX5_HUMAN; Transcription factor PAX 5;
免疫原
- Q02548 PAX5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02548 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T9 | Phosphorylation | Uniprot | |
| T15 | Phosphorylation | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| S133 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| Y179 | Phosphorylation | Uniprot | |
| S180 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S298 | Phosphorylation | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| R377 | Methylation | Uniprot |
研究背景
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
O-glycosylated.
Nucleus.
Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4. Interacts with ETS1, altering its DNA-binding properties.
研究領域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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