SACM1L Antibody - #DF12314
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12314, RRID:AB_2845119.
折りたたみ／展開
Phosphatidylinositide phosphatase SAC1; SAC1; SAC1 suppressor of actin mutations 1-like (yeast); SAC1_HUMAN; SACM1L; suppressor of actin 1; Suppressor of actin mutations 1-like protein;
免疫原
- Q9NTJ5 SAC1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NTJ5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K101 | Ubiquitination | Uniprot | |
| K250 | Ubiquitination | Uniprot | |
| K273 | Ubiquitination | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| S387 | Phosphorylation | Uniprot | |
| K423 | Ubiquitination | Uniprot | |
| K432 | Methylation | Uniprot | |
| K432 | Ubiquitination | Uniprot | |
| K435 | Ubiquitination | Uniprot | |
| K447 | Ubiquitination | Uniprot | |
| K456 | Acetylation | Uniprot | |
| K456 | Ubiquitination | Uniprot | |
| K483 | Ubiquitination | Uniprot | |
| S511 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot |
研究背景
Phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P). Has low activity towards PtdIns(3,5)P2 (By similarity).
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Detected in heart, brain, lung, liver, kidney, pancreas and testis.
研究領域
· Environmental Information Processing > Signal transduction > Phosphatidylinositol signaling system.
· Metabolism > Carbohydrate metabolism > Inositol phosphate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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