SRP14 Antibody - #DF12323
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12323, RRID:AB_2845128.
折りたたみ／展開
18 kDa Alu RNA binding protein; 18 kDa Alu RNA-binding protein; Alu RNA-binding protein, 14-KD subunit; ALURBP; MGC14326; Signal recognition particle 14 kDa protein; signal recognition particle 14kDa (homologous Alu RNA binding protein); SRP 14; SRP14; SRP14_HUMAN;
免疫原
- P37108 SRP14_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P37108 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S25 | Phosphorylation | Uniprot | |
| Y27 | Phosphorylation | Uniprot | |
| T29 | Phosphorylation | Uniprot | |
| Y33 | Phosphorylation | Uniprot | |
| T37 | Phosphorylation | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| T45 | Phosphorylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| K105 | Methylation | Uniprot | |
| T106 | Phosphorylation | Uniprot | |
| K107 | Methylation | Uniprot | |
| K107 | Ubiquitination | Uniprot |
研究背景
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Cytoplasm.
Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
Belongs to the SRP14 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein export.
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