TMSB4X Antibody - #DF12334
(2)
(9)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12334, RRID:AB_2845139.
折りたたみ／展開
Fx; Hematopoietic system regulatory peptide; Prothymosin beta 4; PTMB 4; PTMB4; Seraspenide; T beta 4; T beta-4; TB4X; THYB 4; Thyb4; Thymosin beta 4; Thymosin beta 4 X chromosome; Thymosin beta 4 X linked; TMSB 4; TMSB4; Tmsb4x; TYB4_HUMAN;
免疫原
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
- P62328 TYB4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P62328 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K4 | Acetylation | Uniprot | |
| K4 | Methylation | Uniprot | |
| K4 | Ubiquitination | Uniprot | |
| K12 | Acetylation | Uniprot | |
| K12 | Ubiquitination | Uniprot | |
| K15 | Acetylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| K17 | Acetylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| T21 | Phosphorylation | Uniprot | |
| T23 | Phosphorylation | Uniprot | |
| K26 | Acetylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| K32 | Acetylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| K39 | Acetylation | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| S44 | Phosphorylation | Uniprot |
研究背景
Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.
Cytoplasm>Cytoskeleton.
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
Interacts with SERPINB1 (By similarity). Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X.
Belongs to the thymosin beta family.
研究領域
· Cellular Processes > Cell motility > Regulation of actin cytoskeleton. (View pathway)
参考文献
Application: WB Species: mouse Sample: MSCs and Tβ4-MSCs
Application: WB Species: rat Sample: cortical neurons
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