ARHGDIB Antibody - #DF12349
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12349, RRID:AB_2845154.
折りたたみ／展開
Arhgdib; D4; D4 GDP dissociation inhibitor; GDIA 2; GDIA2; GDID 4; GDID4; GDIR2_HUMAN; GDP dissociation inhibitor D4; LY GDI; Ly-GDI; LYGDI; MGC108926; RAP1GN1; Rho GDI 2; Rho GDI beta; Rho GDI2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP dissociation inhibitor 2; Rho GDP dissociation inhibitor beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta; RhoGDI2;
免疫原
- P52566 GDIR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P52566 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K4 | Acetylation | Uniprot | |
| K4 | Ubiquitination | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| K21 | Acetylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| Y24 | Phosphorylation | P12931 (SRC) , P43405 (SYK) | Uniprot |
| K25 | Acetylation | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| S31 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| K33 | Acetylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| K40 | Acetylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| K47 | Acetylation | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| T51 | Phosphorylation | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| K63 | Acetylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| C76 | S-Nitrosylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K102 | Acetylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K124 | Acetylation | Uniprot | |
| K124 | Ubiquitination | Uniprot | |
| Y130 | Phosphorylation | Uniprot | |
| K135 | Acetylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K138 | Acetylation | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| S145 | Phosphorylation | Uniprot | |
| Y146 | Phosphorylation | Uniprot | |
| Y153 | Phosphorylation | P12931 (SRC) | Uniprot |
| T157 | Phosphorylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| K175 | Acetylation | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| T179 | Phosphorylation | Uniprot | |
| S194 | Phosphorylation | Uniprot | |
| K197 | Acetylation | Uniprot |
研究背景
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates reorganization of the actin cytoskeleton mediated by Rho family members.
Cytoplasm>Cytosol.
Detected in bone marrow, thymus and spleen.
Interacts with RHOA. Interacts with RAC1. Interacts with RAC2. Interacts with CDC42.
Belongs to the Rho GDI family.
研究領域
· Organismal Systems > Nervous system > Neurotrophin signaling pathway. (View pathway)
· Organismal Systems > Excretory system > Vasopressin-regulated water reabsorption.
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