NSDHL Antibody - #DF12432
| 製品: | NSDHL Antibody |
| カタログ: | DF12432 |
| タンパク質の説明: | Rabbit polyclonal antibody to NSDHL |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 42 kDa,40 kDa; 42kD(Calculated). |
| ユニプロット: | Q15738 |
| RRID: | AB_2845237 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12432, RRID:AB_2845237.
折りたたみ／展開
decarboxylating; H105E3; H105e3 protein; NAD(P) dependent steroid dehydrogenase like; NSDHL; NSDHL_HUMAN; Protein H105e3; SDR31E1; Short chain dehydrogenase/reductase family 31E member 1; Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating; Sterol-4-alpha-carboxylate 3-dehydrogenase; XAP104;
免疫原
- Q15738 NSDHL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15738 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T19 | Phosphorylation | Uniprot | |
| T22 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| K31 | Ubiquitination | Uniprot | |
| S87 | Phosphorylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| Y164 | Phosphorylation | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| T284 | Phosphorylation | Uniprot | |
| Y288 | Phosphorylation | Uniprot | |
| K345 | Ubiquitination | Uniprot | |
| Y349 | Phosphorylation | Uniprot | |
| T354 | Phosphorylation | Uniprot |
研究背景
Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Endoplasmic reticulum membrane>Single-pass membrane protein. Lipid droplet.
Note: Trafficking through the Golgi is necessary for ER membrane localization.
Brain, heart, liver, lung, kidney, skin and placenta.
Belongs to the 3-beta-HSD family.
研究領域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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