OXA1L Antibody - #DF12437
| 製品: | OXA1L Antibody |
| カタログ: | DF12437 |
| タンパク質の説明: | Rabbit polyclonal antibody to OXA1L |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 42 kDa; 49kD(Calculated). |
| ユニプロット: | Q15070 |
| RRID: | AB_2845242 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12437, RRID:AB_2845242.
折りたたみ／展開
HSA; Mitochondrial inner membrane protein OXA1L; OXA1; OXA1 like protein; OXA1-like protein; OXA1Hs; Oxa1l; OXA1L_HUMAN; Oxidase (cytochrome c) assembly 1 like; Oxidase assembly 1 like protein; Oxidase assembly 1-like protein;
免疫原
- Q15070 OXA1L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPVAPCCCRPHYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAACTVFARCLIFPLIVTGQREAARIHNHLPEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAETGVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAARGPLRQTFTHNPLLQPGKDNPPNIPSSSSKPKSKYPWHDTLG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15070 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K178 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| T340 | Phosphorylation | Uniprot | |
| K343 | Ubiquitination | Uniprot | |
| K354 | Ubiquitination | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| K366 | Ubiquitination | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| R394 | Methylation | Uniprot | |
| T400 | Phosphorylation | Uniprot | |
| T402 | Phosphorylation | Uniprot | |
| K411 | Ubiquitination | Uniprot |
研究背景
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.
Mitochondrion inner membrane>Multi-pass membrane protein.
Monomer; predominantly monomeric at low salt concentrations. Homooligomer; predominantly homooligomeric at high salt concentrations. Homodimer. Homotetramer. Interacts with MRPL13, MRPL20, MRPL28, MRPL48, MRPL49 and MRPL51. Associates preferentially as a dimer with the large ribosomal subunit 39S of the mitochondrial ribosome.
Belongs to the OXA1/ALB3/YidC family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein export.
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