P4HA2 Antibody - #DF12440
| 製品: | P4HA2 Antibody |
| カタログ: | DF12440 |
| タンパク質の説明: | Rabbit polyclonal antibody to P4HA2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Horse, Sheep, Rabbit, Dog |
| 分子量: | 61 kDa; 61kD(Calculated). |
| ユニプロット: | O15460 |
| RRID: | AB_2845245 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12440, RRID:AB_2845245.
折りたたみ／展開
2-oxoglutarate-4-dioxygenase subunit alpha-2; 4 PH alpha 2; 4-PH alpha-2; C-P4Halpha(II); collagen prolyl 4-hydroxylase alpha(II); P4HA2; P4HA2_HUMAN; procollagen proline, 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase), alpha polypeptide II; procollagen proline, 2 oxoglutarate 4 dioxygenase alpha subunit, isoform 2; Procollagen-proline; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2; Prolyl 4 hydroxylase alpha 2 subunit; Prolyl 4 hydroxylase subunit alpha 2 [Precursor]; Prolyl 4-hydroxylase subunit alpha-2; Prolyl 4-hydroxylase, alpha polypeptide II;
免疫原
- O15460 P4HA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15460 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T31 | Phosphorylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| S43 | Phosphorylation | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| Y79 | Phosphorylation | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| K300 | Ubiquitination | Uniprot | |
| K328 | Sumoylation | Uniprot | |
| K328 | Ubiquitination | Uniprot | |
| S346 | Phosphorylation | Uniprot | |
| K383 | Ubiquitination | Uniprot | |
| Y421 | Phosphorylation | Uniprot | |
| T441 | Phosphorylation | Uniprot | |
| K443 | Ubiquitination | Uniprot | |
| T447 | Phosphorylation | Uniprot | |
| T482 | Phosphorylation | Uniprot | |
| Y487 | Phosphorylation | Uniprot |
研究背景
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Endoplasmic reticulum lumen.
Heterotetramer of two alpha-2 chains and two beta chains (the beta chain is the multi-functional PDI).
Belongs to the P4HA family.
研究領域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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