SAT1 Antibody - #DF12469
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(1)
| 製品: | SAT1 Antibody |
| カタログ: | DF12469 |
| タンパク質の説明: | Rabbit polyclonal antibody to SAT1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 25-30 kDa; 20kD(Calculated). |
| ユニプロット: | P21673 |
| RRID: | AB_2845274 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12469, RRID:AB_2845274.
折りたたみ／展開
DC21; Diamine acetyltransferase 1; Diamine N acetyltransferase 1; EC 2.3.1.57; KFSD; KFSDX; Polyamine N acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SAT; SAT1; SAT1_HUMAN; Spermidine/spermine N(1) acetyltransferase 1; Spermidine/spermine N(1)-acetyltransferase 1; Spermidine/spermine N1 acetyltransferase 1; Spermidine/spermine N1 acetyltransferase alpha; SSAT 1; SSAT; SSAT-1;
免疫原
- P21673 SAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P21673 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Ubiquitination | Uniprot | |
| T10 | Phosphorylation | P19784 (CSNK2A2) , P68400 (CSNK2A1) | Uniprot |
| K22 | Ubiquitination | Uniprot | |
| K26 | Acetylation | Uniprot | |
| Y27 | Phosphorylation | Uniprot | |
| Y77 | Phosphorylation | Uniprot | |
| Y78 | Phosphorylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| Y90 | Phosphorylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| S146 | Phosphorylation | P19784 (CSNK2A2) , P68400 (CSNK2A1) | Uniprot |
| S149 | Phosphorylation | P19784 (CSNK2A2) , P68400 (CSNK2A1) | Uniprot |
| K158 | Ubiquitination | Uniprot | |
| K161 | Ubiquitination | Uniprot | |
| K166 | Ubiquitination | Uniprot |
研究背景
Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.
Cytoplasm.
Homodimer.
Belongs to the acetyltransferase family.
研究領域
· Cellular Processes > Cell growth and death > Ferroptosis. (View pathway)
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
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