製品: Peripherin Antibody
カタログ: AF0242
タンパク質の説明: Rabbit polyclonal antibody to Peripherin
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Bovine, Horse, Rabbit, Dog
分子量: 55kDa; 54kD(Calculated).
ユニプロット: P41219
RRID: AB_2833417

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Bovine(91%), Horse(93%), Rabbit(86%), Dog(86%)
クローナリティ:
Polyclonal
特異性:
Peripherin Antibody detects endogenous levels of total Peripherin.
RRID:
AB_2833417
引用形式: Affinity Biosciences Cat# AF0242, RRID:AB_2833417.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

NEF 4; NEF4; Neurofilament 4 (57kD); Neurofilament 4; Perf; PERI_HUMAN; Peripherin; PRPH 1; prph; PRPH1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
peripherin Class-III neuronal intermediate filament protein. Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.
タンパク質配列:
MSHHPSGLRAGFSSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSELDKSSAHSY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
93
Bovine
91
Dog
86
Rabbit
86
Pig
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P41219 基板として

Site PTM Type Enzyme
S13 Phosphorylation
Y17 Phosphorylation
S28 Phosphorylation
S50 Phosphorylation
S59 Phosphorylation P31749 (AKT1)
S62 Phosphorylation
S75 Phosphorylation
K98 Methylation
Y287 Phosphorylation
K288 Acetylation
K288 Ubiquitination
K290 Ubiquitination
K398 Acetylation
K398 Sumoylation
K398 Ubiquitination
S405 Phosphorylation
S413 Phosphorylation
T421 Phosphorylation
Y470 Phosphorylation

研究背景

機能:

Class-III neuronal intermediate filament protein.

タンパク質ファミリー:

Belongs to the intermediate filament family.

研究領域

· Human Diseases > Neurodegenerative diseases > Amyotrophic lateral sclerosis (ALS).

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