製品: MTCH1 Antibody
カタログ: DF12524
タンパク質の説明: Rabbit polyclonal antibody to MTCH1
アプリケーション: WB
反応性: Human
予測: Pig, Bovine
分子量: 42 kDa; 42kD(Calculated).
ユニプロット: Q9NZJ7
RRID: AB_2845486

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(100%), Bovine(100%)
クローナリティ:
Polyclonal
特異性:
MTCH1 Antibody detects endogenous levels of total MTCH1.
RRID:
AB_2845486
引用形式: Affinity Biosciences Cat# DF12524, RRID:AB_2845486.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cell proliferation inducing protein 60; CGI64; Mitochondrial carrier homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin associated protein; Presenilin-associated protein; PSAP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NZJ7 MTCH1_HUMAN:

Widely expressed with a predominant expression in brain.

タンパク質配列:
MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NZJ7 基板として

Site PTM Type Enzyme
S4 Phosphorylation
R29 Methylation
S61 Phosphorylation
S96 Phosphorylation
K125 Ubiquitination
Y128 Phosphorylation
S158 Phosphorylation
K171 Ubiquitination
K184 Ubiquitination
K188 Ubiquitination
S381 Phosphorylation
S382 Phosphorylation
S384 Phosphorylation

研究背景

機能:

Potential mitochondrial transporter. May play a role in apoptosis.

細胞の位置付け:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed with a predominant expression in brain.

サブユニット構造:

Interacts with PSEN1.

タンパク質ファミリー:

Belongs to the mitochondrial carrier (TC 2.A.29) family.

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