PERM Antibody - #DF12528
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| 製品: | PERM Antibody |
| カタログ: | DF12528 |
| タンパク質の説明: | Rabbit polyclonal antibody to PERM |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 84 kDa; 84kD(Calculated). |
| ユニプロット: | P05164 |
| RRID: | AB_2845490 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12528, RRID:AB_2845490.
折りたたみ／展開
84 kDa myeloperoxidase; 89 kDa myeloperoxidase; EC 1.11.1.7; EC1.11.2.2; fj80f04; MPO; mpx; myeloid-specific peroxidase; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain; PERM_HUMAN; wu:fj80f04;
免疫原
- P05164 PERM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P05164 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K103 | Acetylation | Uniprot | |
| N139 | N-Glycosylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| N323 | N-Glycosylation | Uniprot | |
| N355 | N-Glycosylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| N391 | N-Glycosylation | Uniprot | |
| T428 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| Y500 | Phosphorylation | Uniprot | |
| Y516 | Phosphorylation | Uniprot | |
| S528 | Phosphorylation | Uniprot | |
| K625 | Sumoylation | Uniprot | |
| S720 | Phosphorylation | Uniprot | |
| Y723 | Phosphorylation | Uniprot | |
| N729 | N-Glycosylation | Uniprot |
研究背景
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Lysosome.
Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain.
Belongs to the peroxidase family. XPO subfamily.
研究領域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
· Human Diseases > Cancers: Specific types > Acute myeloid leukemia. (View pathway)
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
参考文献
Application: WB Species: Rat Sample: Liver
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