CPOX Antibody - #DF12588
| 製品: | CPOX Antibody |
| カタログ: | DF12588 |
| タンパク質の説明: | Rabbit polyclonal antibody to CPOX |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Rabbit |
| 分子量: | 36 kDa; 50kD(Calculated). |
| ユニプロット: | P36551 |
| RRID: | AB_2845550 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12588, RRID:AB_2845550.
折りたたみ／展開
Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial;
免疫原
- P36551 HEM6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P36551 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S112 | Phosphorylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| R298 | Methylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| K404 | Acetylation | Uniprot | |
| K404 | Ubiquitination | Uniprot | |
| T409 | Phosphorylation | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| S420 | Phosphorylation | Uniprot | |
| T424 | Phosphorylation | Uniprot | |
| K438 | Ubiquitination | Uniprot |
研究背景
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Mitochondrion intermembrane space.
Homodimer.
Belongs to the aerobic coproporphyrinogen-III oxidase family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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