製品: CTPS2 Antibody
カタログ: DF12590
タンパク質の説明: Rabbit polyclonal antibody to CTPS2
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 66 kDa; 66kD(Calculated).
ユニプロット: Q9NRF8
RRID: AB_2845552

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
CTPS2 Antibody detects endogenous levels of total CTPS2.
RRID:
AB_2845552
引用形式: Affinity Biosciences Cat# DF12590, RRID:AB_2845552.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CTP synthase 2; CTP synthase II; CTP synthetase 2; CTPS2; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2; FLJ43358; MGC32997; PYRG2_HUMAN; UTP--ammonia ligase 2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRYSDASDDSFSEPRIAELEIS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NRF8 基板として

Site PTM Type Enzyme
S12 Phosphorylation
Y53 Phosphorylation
K92 Ubiquitination
K100 Ubiquitination
K169 Methylation
T189 Phosphorylation
K195 Ubiquitination
R205 Methylation
S261 Phosphorylation
K264 Ubiquitination
S277 Phosphorylation
Y336 Phosphorylation
K353 Ubiquitination
K360 Ubiquitination
T378 Phosphorylation
R389 Methylation
K466 Ubiquitination
S562 Phosphorylation
S563 Phosphorylation
S564 Phosphorylation
R566 Methylation
Y567 Phosphorylation
S568 Phosphorylation P48729 (CSNK1A1)
S571 Phosphorylation
S574 Phosphorylation
S576 Phosphorylation

研究背景

機能:

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.

タンパク質ファミリー:

Belongs to the CTP synthase family.

研究領域

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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