FATP4 Antibody - #DF12606
| 製品: | FATP4 Antibody |
| カタログ: | DF12606 |
| タンパク質の説明: | Rabbit polyclonal antibody to FATP4 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus |
| 分子量: | 70 kDa; 72kD(Calculated). |
| ユニプロット: | Q6P1M0 |
| RRID: | AB_2845568 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12606, RRID:AB_2845568.
折りたたみ／展開
ACSVL 4; ACSVL4; EC 6.2.1; FATP 4; FATP4; Fatty acid transport protein 4; Fatty acid transport protein4; IPS; Long chain fatty acid transport protein 4; Long chain fatty acid transport protein4; OTTHUMP00000022264; S27A4; SLC27 A4; SLC27A 4; Solute carrier family 27 (fatty acid transporter) member 4; Solute carrier family 27 member 4; Solute carrier family 27 member4;
免疫原
Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tissue.
- Q6P1M0 S27A4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEKL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6P1M0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| T75 | Phosphorylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| K227 | Ubiquitination | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| Y243 | Phosphorylation | Uniprot | |
| Y245 | Phosphorylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| Y264 | Phosphorylation | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| T425 | Phosphorylation | Uniprot | |
| K454 | Ubiquitination | Uniprot | |
| Y463 | Phosphorylation | Uniprot | |
| K471 | Acetylation | Uniprot | |
| K471 | Ubiquitination | Uniprot | |
| K475 | Ubiquitination | Uniprot | |
| K512 | Ubiquitination | Uniprot | |
| S555 | Phosphorylation | Uniprot | |
| K571 | Ubiquitination | Uniprot | |
| Y576 | Phosphorylation | Uniprot | |
| K595 | Ubiquitination | Uniprot | |
| K598 | Ubiquitination | Uniprot | |
| K603 | Ubiquitination | Uniprot | |
| K612 | Ubiquitination | Uniprot | |
| K622 | Ubiquitination | Uniprot | |
| K642 | Ubiquitination | Uniprot |
研究背景
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
Membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane.
Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tissue.
Belongs to the ATP-dependent AMP-binding enzyme family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Insulin resistance.
· Organismal Systems > Endocrine system > PPAR signaling pathway.
· Organismal Systems > Digestive system > Fat digestion and absorption.
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