GCDH Antibody - #DF12614
| 製品: | GCDH Antibody |
| カタログ: | DF12614 |
| タンパク質の説明: | Rabbit polyclonal antibody to GCDH |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 48 kDa; 48kD(Calculated). |
| ユニプロット: | Q92947 |
| RRID: | AB_2845576 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12614, RRID:AB_2845576.
折りたたみ／展開
ACAD5; EC 1.3.99.7; GCD; Gcdh; GCDH_HUMAN; Glutaryl CoA dehydrogenase; Glutaryl CoA dehydrogenase, mitochondrial; Glutaryl Coenzyme A dehydrogenase; Glutaryl-CoA dehydrogenase; mitochondrial; MS781;
免疫原
- Q92947 GCDH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTASK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92947 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K32 | Ubiquitination | Uniprot | |
| R88 | Methylation | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| S255 | Phosphorylation | Uniprot | |
| R319 | Methylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K377 | Ubiquitination | Uniprot | |
| Y398 | Phosphorylation | Uniprot | |
| K438 | Acetylation | Uniprot |
研究背景
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.
Mitochondrion matrix.
Isoform Long and isoform Short are expressed in fibroblasts and liver.
Homotetramer.
Belongs to the acyl-CoA dehydrogenase family.
研究領域
· Metabolism > Lipid metabolism > Fatty acid degradation.
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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